Index › Foie, voies biliaires, pancréas et glandes endocrines › Hepatic stellate cell (quiescent)

Hepatic stellate cell (quiescent)

Liver-specific pericyte in the space of Disse storing retinoids and maintaining ECM; primary source of myofibroblasts.

Synonymes : Ito cell, Perisinusoidal cell, Vitamin A-storing cell

Tissus : liver, liver (sinusoids)

Cell Ontology : hepatic stellate cell · CL:0000632 (correspondance exacte) — A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literatu

Marqueurs (13)

Sous-types

• Quiescent hepatic stellate cell (human snRNA-seq Mes-1/Mes-5)
• Portal vein-associated HSC (PaHSC)
• Central vein-associated HSC (CaHSC)
• Activated HSC / scar-associated myofibroblast
• Activated hepatic stellate cell (myofibroblast)

Données curées avec références PubMed/DOI, licence CC BY 4.0. « Spécifique » est calculé sur la couverture de cet atlas : vérifiez dans la littérature citée. Version interactive avec filtres et comparaison.