Index › Mésenchymateux – stromal, squelettique et adipeux › Mesenchymal stromal cell (MSC, ISCT definition) › Bone marrow MSC
Bone marrow MSC
MSC (CFU-F) population of the bone marrow stroma, enriched in perivascular LEPR+/CXCL12-high cells in mouse and CD271+/CD146+ cells in human.
Marqueurs (12)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| LEPR | positif | Leptin receptor | mRNA, protein | défini | mouse | 24953181 17956733 |
| CXCL12 | positif | CXCL12 (SDF-1) | mRNA, protein | enrichi | human, mouse | 24953181 20850355 30971824 |
| KITLG | positif | SCF (KIT ligand) | mRNA, protein | enrichi | mouse | 24953181 30971824 |
| NGFR | positif | CD271 (LNGFR) | mRNA, protein | enrichi | human | 31130381 |
| MCAM | positif | CD146 (MCAM) | mRNA, protein | sous-ensemble | human | 17956733 18786417 |
| NES | positif | Nestin | mRNA, protein | sous-ensemble | mouse | 24953181 |
| PDGFRA | positif | PDGFR-alpha | mRNA, protein | sous-ensemble | human, mouse | 24823377 |
| PDGFRB | positif | PDGFR-beta | mRNA, protein | sous-ensemble | human, mouse | 31130381 |
| VCAM1 | positif | CD106 (VCAM-1) | mRNA, protein | sous-ensemble | human, mouse | 30971824 |
| PECAM1 | négatif | CD31 | mRNA, protein | exclusion | human, mouse | 16923606 24953181 |
| PTPRC | négatif | CD45 | mRNA, protein | exclusion | human, mouse | 16923606 24953181 |
| TEK | négatif | Tie2 | mRNA, protein | exclusion | mouse | 25594184 |