Index › Mésenchymateux – stromal, squelettique et adipeux › Chondroprogenitor / condensing mesenchyme › Chondrocyte (growth plate / articular) › Hypertrophic chondrocyte

Hypertrophic chondrocyte

Terminally differentiating enlarged chondrocyte producing type X collagen and mineralised matrix, preceding vascular invasion.

Tissus : growth plate, fracture callus

Cell Ontology : hypertrophic chondrocyte · CL:0000743 (correspondance exacte) — A chondrocyte that is part of the hypertrophic cartilage zone. This cell is significantly enlarged and characterised by high expression of type X collagen (COL10A1) in both humans and mice. It actively coordinates endochondral ossification by mineralising the extracellular matrix, attracting blood vessels via angiogenic signalling, and mediating the transition from cartilage to bone - often by tra

Marqueurs (10)

Données curées avec références PubMed/DOI, licence CC BY 4.0. « Spécifique » est calculé sur la couverture de cet atlas : vérifiez dans la littérature citée. Version interactive avec filtres et comparaison.