Index › Mésenchymateux – stromal, squelettique et adipeux › Skeletal stem cell (SSC)
Skeletal stem cell (SSC)
Self-renewing multipotent stem cell that generates bone, cartilage and stroma, defined by prospective isolation in mouse and human.
Marqueurs (11)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| CD164 | positif | CD164 | protein | enrichi | human | 30241615 |
| CD200 | positif | CD200 | protein | enrichi | mouse | 25594184 |
| ITGAV | positif | CD51 (integrin alpha-V) | protein | enrichi | mouse | 25594184 |
| NT5E | positif | CD73 | protein | enrichi | human | 30241615 |
| PDPN | positif | Podoplanin | mRNA, protein | enrichi | human, mouse | 30241615 |
| ENG | négatif | CD105 | protein | exclusion | mouse | 25594184 |
| GYPA | négatif | Ter119 (Ly76) / glycophorin A | protein | exclusion | human, mouse | 25594184 30241615 |
| MCAM | négatif | CD146 | protein | exclusion | human | 30241615 |
| PECAM1 | négatif | CD31 | protein | exclusion | human | 30241615 |
| PTPRC | négatif | CD45 | protein | exclusion | human, mouse | 25594184 30241615 |
| THY1 | négatif | CD90 | protein | exclusion | mouse | 25594184 |
Sous-types
- Mouse skeletal stem cell (mSSC)
- Human skeletal stem cell (hSSC)
- Gremlin1+ skeletal stem cell
- Growth plate resting-zone skeletal stem cell (PTHrP+)
- Periosteal stem cell (CTSK+)
- LepR+ perivascular stromal cell (bone marrow)
- CXCL12-abundant reticular (CAR) cell
- Arteriolar NG2+ pericyte (bone marrow)
- Bone marrow fibro-like / chondro-like stromal cell
- Osteoprogenitor