Index › Muscle, cœur, système vasculaire et lymphatique, séreuses › Smooth muscle cell (pan-lineage) › Vascular smooth muscle cell, synthetic / dedifferentiated › Modulated SMC, LGALS3+ transitional (pioneer) cell › Modulated SMC, macrophage-like
Modulated SMC, macrophage-like
SMC-derived cells expressing macrophage markers after cholesterol loading with KLF4-dependent reprogramming (also questioned in human data).
Marqueurs (5)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| KLF4 | positif | KLF4 | mRNA, protein | défini | human, mouse | 25985364 |
| ACTA2 | négatif | alpha-SMA | mRNA, protein | enrichi | human, mouse | 25985364 |
| LGALS3 | positif | Galectin-3 | mRNA, protein | enrichi | human, mouse | 25985364 25573853 |
| MYH11 | négatif | SM-MHC | mRNA, protein | enrichi | human, mouse | 25985364 32962412 |
| CD68 | positif | CD68 | mRNA, protein | sous-ensemble | human, mouse | 25573853 |