Index › Oncologie – cellules malignes et pathologiques › Carcinoma (epithelial malignancy)
Carcinoma (epithelial malignancy)
Malignant epithelial tumour; pan-epithelial keratin and EpCAM expression, with lineage-specific transcription factors defining subtypes.
Marqueurs (5)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| CDH1 | positif | E-cadherin | mRNA, protein | pan-lignée | human | 37258682 29198524 |
| EPCAM | positif | EpCAM | mRNA, protein | pan-lignée | human | 37258682 29198524 |
| KRT8 | positif | CK8/18 | mRNA, protein | pan-lignée | human | 37258682 29198524 |
| PTPRC | négatif | CD45 | protein | exclusion | human | 37258682 29198524 |
| VIM | négatif | Vimentin | protein | exclusion | human | 37258682 29198524 |
Sous-types
- Basal cell carcinoma (corrected references)
- Merkel cell carcinoma (corrected references)
- Papillary thyroid carcinoma (corrected references)
- Follicular thyroid carcinoma (corrected references)
- Medullary thyroid carcinoma (corrected references)
- Anaplastic thyroid carcinoma (corrected references)
- Malignant mesothelioma (corrected references)
- High-grade neuroendocrine carcinoma (corrected references)
- Small intestine neuroendocrine tumour (midgut carcinoid)
- Adrenocortical carcinoma
- Hepatoblastoma
- Claudin-low breast cancer (intrinsic subtype)
- HeLa cell line
- MCF7 cell line
- Pancreatic neuroendocrine tumour (corrected references)
- Lung adenocarcinoma
- Lung squamous cell carcinoma
- Small cell lung carcinoma
- Lung carcinoid / neuroendocrine tumour
- Colorectal adenocarcinoma
- Gastric adenocarcinoma
- Esophageal squamous cell carcinoma
- Esophageal adenocarcinoma
- Pancreatic ductal adenocarcinoma
- Hepatocellular carcinoma
- Cholangiocarcinoma
- Breast carcinoma luminal A
- Breast carcinoma luminal B
- HER2-enriched breast carcinoma
- Triple-negative / basal-like breast carcinoma
- Clear cell renal cell carcinoma
- Chromophobe renal cell carcinoma
- Papillary renal cell carcinoma
- Prostate adenocarcinoma (acinar)
- Neuroendocrine prostate cancer
- Urothelial carcinoma luminal
- Urothelial carcinoma basal/squamous
- High-grade serous ovarian carcinoma
- Endometrial endometrioid carcinoma
- Uterine serous carcinoma
- Cervical squamous cell carcinoma
- Cervical adenocarcinoma (HPV-associated)
- Head and neck squamous cell carcinoma
- Cutaneous squamous cell carcinoma
- Adenoid cystic carcinoma