Index › Peau, annexes cutanées et organes sensoriels (dérivés ectodermiques de surface) › Epidermal keratinocyte (pan)
Epidermal keratinocyte (pan)
Epithelial cell of the interfollicular epidermis and its appendages, defined by keratin expression and ectodermal origin.
Marqueurs (9)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| CDH1 | positif | E-cadherin | mRNA, protein | pan-lignée | human, mouse | 30332640 30355494 |
| EPCAM | positif | EPCAM | mRNA, protein | pan-lignée | human, mouse | 30355494 30332640 |
| KRT14 | positif | KRT14 | mRNA, protein | pan-lignée | human, mouse | 30355494 32843640 18461349 |
| KRT5 | positif | KRT5 | mRNA, protein | pan-lignée | human, mouse | 30355494 32843640 18461349 |
| TP63 | positif | p63 | mRNA, protein | pan-lignée | human, mouse | 32843640 22940863 |
| COL1A1 | négatif | COL1A1 | mRNA | exclusion | human, mouse | 33479125 35549404 |
| PDGFRA | négatif | PDGFRA | mRNA | exclusion | human, mouse | 33479125 30332640 |
| PECAM1 | négatif | CD31 | mRNA, protein | exclusion | human, mouse | 33479125 35549404 |
| PTPRC | négatif | CD45 | mRNA, protein | exclusion | human, mouse | 30355494 33479125 |
Sous-types
- Activated / wound-associated keratinocyte (KRT6/16/17-high)
- Isthmus keratinocyte (hair follicle)
- Infundibulum keratinocyte (hair follicle)
- Sebaceous duct keratinocyte
- Interfollicular epidermal basal keratinocyte
- Differentiating (committed) basal/early suprabasal keratinocyte
- Spinous keratinocyte
- Granular keratinocyte
- Cornified keratinocyte (corneocyte)
- Junctional zone / infundibular keratinocyte
- Hair follicle bulge stem cell
- Lgr6+ upper isthmus stem cell
- Outer root sheath cell
- Hair matrix transit-amplifying progenitor
- Sebaceous gland progenitor (BLIMP1+ / LRIG1+)
- Merkel cell