Index › Hématopoïétique – myéloïde › Hematopoietic stem and progenitor cell (lineage-negative) › Common myeloid progenitor (CMP) › Granulocyte-monocyte progenitor (GMP) › Committed neutrophil progenitor (preNeu / proNeu)
Committed neutrophil progenitor (preNeu / proNeu)
Proliferative committed precursor derived from the GMP that gives rise only to neutrophils and requires C/EBPepsilon.
Marqueurs (8)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| CEBPE | positif | C/EBPepsilon | mRNA | défini | mouse | 29466759 |
| CXCR4 | positif | CXCR4 | protein | enrichi | mouse | 29466759 |
| ELANE | positif | neutrophil elastase | mRNA | enrichi | human, mouse | 32719519 32579887 |
| ITGAM | positif | CD11b | protein | enrichi | mouse | 29466759 |
| KIT | positif | CD117 | protein | enrichi | mouse | 29466759 32579887 |
| LY6G | négatif | Ly6G | protein | enrichi | mouse | 29466759 17884993 |
| MPO | positif | myeloperoxidase | mRNA | enrichi | human, mouse | 32719519 32579887 |
| LY6A | négatif | Sca-1 | protein | exclusion | mouse | 32579887 |