Index › Hématopoïétique – myéloïde › Hematopoietic stem and progenitor cell (lineage-negative) › Common myeloid progenitor (CMP) › Megakaryocyte-erythroid progenitor (MEP) › Burst-forming unit erythroid (BFU-E) › Colony-forming unit erythroid (CFU-E) › Proerythroblast › Basophilic erythroblast › Polychromatic erythroblast › Orthochromatic erythroblast

Orthochromatic erythroblast

Final nucleated erythroblast, about to extrude its nucleus; alpha4 integrin low.

Synonymes : normoblast

Tissus : bone marrow

Cell Ontology : orthochromatic erythroblast · CL:0000552 (correspondance exacte) — The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homoge

Marqueurs (4)

Sous-types

• Mouse EryC (CD44-low erythroblast)
• Reticulocyte

Données curées avec références PubMed/DOI, licence CC BY 4.0. « Spécifique » est calculé sur la couverture de cet atlas : vérifiez dans la littérature citée. Version interactive avec filtres et comparaison.