Index › Hématopoïétique – myéloïde › Hematopoietic stem and progenitor cell (lineage-negative) › Macrophage-DC progenitor (MDP) › Common dendritic cell progenitor (CDP) › Pre-DC (circulating DC precursor)
Pre-DC (circulating DC precursor)
Circulating committed precursor of cDC1 and cDC2; in human contained in the AXL+SIGLEC6+ DC compartment.
Marqueurs (8)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| AXL | positif | AXL | mRNA, protein | enrichi | human | 28428369 28473638 |
| FLT3 | positif | CD135 | protein | enrichi | human, mouse | 25687281 17922015 |
| IL3RA | positif | CD123 | mRNA, protein | enrichi | human | 28473638 28428369 25687281 |
| ITGAX | négatif | CD11c | protein | enrichi | human, mouse | 17922015 25687281 |
| SIGLEC6 | positif | Siglec-6 | mRNA, protein | enrichi | human | 28428369 28473638 |
| CD22 | positif | CD22 | mRNA, protein | sous-ensemble | human | 28428369 |
| PTPRC | positif | CD45RA | protein | sous-ensemble | human | 25687281 |
| CLEC4C | négatif | BDCA-2 | protein | exclusion | human | 28473638 28428369 |