Index › Lymphoïde › Lymphocyte (lymphoid lineage root) › T cell (pan-T) › CD4 T cell › Regulatory T cell (Treg) › Th1-like Treg (T-bet+CXCR3+)
Th1-like Treg (T-bet+CXCR3+)
Foxp3+ Treg that upregulates T-bet and CXCR3 during type 1 inflammation; IFN-g can drive loss of suppression (Treg fragility).
Marqueurs (9)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| CXCR3 | positif | CXCR3 | protein | défini | human, mouse | 19412181 |
| FOXP3 | positif | FOXP3 | mRNA, protein | défini | human, mouse | 19412181 |
| TBX21 | positif | TBX21 | mRNA, protein | défini | human, mouse | 19412181 |
| CTLA4 | positif | CTLA4 | mRNA, protein | enrichi | human, mouse | 19412181 |
| IFNGR1 | positif | IFNGR1 | mRNA | enrichi | human, mouse | 28552348 |
| IL2RA | positif | CD25 | protein | enrichi | human, mouse | 19412181 |
| CCR5 | positif | CCR5 | protein | sous-ensemble | human | 22438251 |
| IL10 | positif | IL10 | mRNA, protein | sous-ensemble | human, mouse | 19412181 |
| IFNG | négatif | IFNG | mRNA, protein | exclusion | human, mouse | 28552348 |