Index › Lymphoïde › Lymphocyte (lymphoid lineage root) › T cell (pan-T) › CD4 T cell › Regulatory T cell (Treg) › Thymic-derived Treg (nTreg / tTreg)
Thymic-derived Treg (nTreg / tTreg)
Treg selected in the thymus by high-affinity self-recognition; Helios+ Nrp1+ in mouse.
Marqueurs (9)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| FOXP3 | positif | FOXP3 | mRNA, protein | défini | human, mouse | 12522256 15780990 |
| CTLA4 | positif | CTLA4 | mRNA, protein | enrichi | human, mouse | 12612578 |
| IKZF2 | positif | Helios | mRNA, protein | enrichi | human, mouse | 20181882 |
| IL2RA | positif | CD25 | mRNA, protein | enrichi | human, mouse | 7636184 12522256 |
| IL7R | négatif | CD127 | mRNA, protein | enrichi | human | 16818678 16818676 |
| NRP1 | positif | Neuropilin-1 | mRNA, protein | enrichi | mouse | 22966001 |
| TNFRSF18 | positif | GITR | mRNA, protein | enrichi | human, mouse | 12612578 |
| CCR7 | positif | CCR7 | mRNA, protein | sous-ensemble | human | 19464196 |
| PTPRC | positif | CD45RA | protein | sous-ensemble | human | 19464196 |