Index › Mésenchymateux – stromal, squelettique et adipeux › Fibroblast (pan-tissue)

Fibroblast (pan-tissue)

Collagen- and ECM-producing stromal cell of connective tissue; defined by mesenchymal/ECM genes and absence of hematopoietic, epithelial and endothelial markers.

Synonymes : Stromal fibroblast

Tissus : connective tissue, all organs

Cell Ontology : fibroblast · CL:0000057 (correspondance exacte) — A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.

Marqueurs (13)

Sous-types

• SFRP2+/DPP4+ dermal fibroblast
• FMO1+/LSP1+ dermal fibroblast
• COL11A1+ dermal fibroblast
• PRG4+ dermal fibroblast
• CRABP1+ dermal fibroblast
• En1-lineage-positive scarring dermal fibroblast (mouse)
• En1-lineage-negative dermal fibroblast (mouse)
• Human lung lipofibroblast
• PTGS2+ pericryptal fibroblast (mouse intestine)
• WNT2B+/RSPO3+ colonic fibroblast
• WNT5B+ colonic fibroblast
• Mouse organ-resident fibroblast (heart, skeletal muscle, intestine, bladder)
• Universal fibroblast (PI16+ / DPT+)
• CCL19+ fibroblast (lymphoid-supportive)
• LRRC15+ myofibroblast
• Myofibroblast
• Cancer-associated fibroblast (CAF)
• Papillary dermal fibroblast
• Reticular dermal fibroblast
• Lung alveolar fibroblast
• Lung adventitial fibroblast
• Lung peribronchial fibroblast
• Inflammatory fibroblast (colon, ulcerative colitis)
• Intestinal myofibroblast / pericryptal stromal cell
• Liver portal fibroblast

Données curées avec références PubMed/DOI, licence CC BY 4.0. « Spécifique » est calculé sur la couverture de cet atlas : vérifiez dans la littérature citée. Version interactive avec filtres et comparaison.