Index › Hématopoïétique – myéloïde › Hematopoietic stem and progenitor cell (lineage-negative) › Common myeloid progenitor (CMP) › Granulocyte-monocyte progenitor (GMP) › Mast cell progenitor (MCP) › Mast cell › Mucosal-type mast cell (MCT) › Intraepithelial tryptase-only (MCT) airway mast cell, T2 inflammation
Intraepithelial tryptase-only (MCT) airway mast cell, T2 inflammation
Tryptase+ chymase- epithelial MC expanded in type-2 airway disease (CRSwNP, asthma), with a distinct cell-surface and transcript effector program.
Marqueurs (5)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| TPSAB1 | positif | Tryptase | mRNA, protein | défini | human | 33637594 |
| CPA3 | positif | Carboxypeptidase A3 | mRNA, protein | enrichi | human | 33637594 |
| KIT | positif | CD117 | protein | pan-lignée | human | 33637594 |
| CMA1 | négatif | Chymase | mRNA, protein | exclusion | human | 33637594 |
| CTSG | négatif | Cathepsin G | mRNA, protein | exclusion | human | 33637594 |