Index › Hématopoïétique – myéloïde › Hematopoietic stem and progenitor cell (lineage-negative) › Common myeloid progenitor (CMP) › Granulocyte-monocyte progenitor (GMP) › Mast cell progenitor (MCP) › Mast cell › Connective-tissue-type mast cell (MCTC) › MRGPRX2+/MrgprB2+ connective-tissue mast cell
MRGPRX2+/MrgprB2+ connective-tissue mast cell
Connective-tissue mast cell expressing MRGPRX2 (mouse MrgprB2), activated by basic secretagogues/neuropeptides and many peptidergic drugs; in mouse arises in utero independent of BM.
Marqueurs (7)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| CMA1 | positif | Chymase | mRNA, protein | défini | human, mouse | 33637594 3520574 |
| MRGPRX2 | positif | MRGPRX2 | mRNA, protein | défini | human, mouse | 25517090 37462672 |
| CPA3 | positif | Carboxypeptidase A3 | mRNA, protein | enrichi | human, mouse | 33637594 27135604 |
| CTSG | positif | Cathepsin G | mRNA, protein | enrichi | human | 33637594 |
| TPSAB1 | positif | Tryptase | mRNA, protein | enrichi | human, mouse | 33637594 3520574 |
| FCER1A | positif | FceRI alpha | mRNA, protein | pan-lignée | human, mouse | 33637594 27135604 |
| KIT | positif | CD117 | mRNA, protein | pan-lignée | human, mouse | 27135604 37462672 |