Index › Mésenchymateux – stromal, squelettique et adipeux › Fibroblast (pan-tissue) › Cancer-associated fibroblast (CAF) › Inflammatory CAF (iCAF)
Inflammatory CAF (iCAF)
Alpha-SMA-low CAF distant from tumour cells secreting IL-6, LIF and chemokines.
Marqueurs (12)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| ACTA2 | négatif | alpha-SMA | mRNA, protein | enrichi | human, mouse | 28232471 31197017 |
| CLEC3B | positif | Tetranectin | mRNA | enrichi | human, mouse | 31197017 |
| CXCL1 | positif | CXCL1 | mRNA | enrichi | human, mouse | 28232471 |
| CXCL12 | positif | CXCL12 | mRNA | enrichi | human, mouse | 31197017 |
| CXCL12 | positif | SDF-1 | mRNA | enrichi | human | 28232471 36333338 |
| DPT | positif | Dermatopontin | mRNA | enrichi | human, mouse | 31197017 |
| HAS1 | positif | Hyaluronan synthase 1 | mRNA | enrichi | human, mouse | 31197017 |
| IL1R1 | positif | IL1R1 | mRNA | enrichi | human, mouse | 28232471 |
| IL6 | positif | IL-6 | mRNA, protein | enrichi | human, mouse | 28232471 31197017 |
| LIF | positif | LIF | mRNA | enrichi | human, mouse | 28232471 31197017 |
| PDGFRA | positif | PDGFR-alpha | mRNA, protein | enrichi | human, mouse | 28232471 |
| ACTA2 | négatif | alpha-SMA | protein | exclusion | human | 28232471 |