Index › Hématopoïétique – myéloïde › Hematopoietic stem and progenitor cell (lineage-negative) › Common myeloid progenitor (CMP) › Granulocyte-monocyte progenitor (GMP) › Committed neutrophil progenitor (preNeu / proNeu) › Neutrophil promyelocyte › Neutrophil myelocyte / metamyelocyte › Immature (band) neutrophil › Mature neutrophil › Tumor-associated neutrophil, N1 (anti-tumor), mouse
Tumor-associated neutrophil, N1 (anti-tumor), mouse
Hypersegmented, cytotoxic CD11b+Ly6G+ TAN that accumulates after TGF-b blockade; the N1/N2 dichotomy is a model, not a validated human lineage.
Marqueurs (5)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| TNF | positif | TNF-alpha | mRNA, protein | enrichi | mouse | 19732719 |
| CCL3 | positif | MIP-1a | mRNA | sous-ensemble | mouse | 19732719 |
| ICAM1 | positif | ICAM-1 | mRNA, protein | sous-ensemble | mouse | 19732719 |
| ITGAM | positif | CD11b | protein | pan-lignée | mouse | 19732719 |
| LY6G | positif | Ly6G | protein | pan-lignée | mouse | 19732719 |