Index › Lymphoïde › Lymphocyte (lymphoid lineage root) › B cell (pan-B) › Plasma cell (long-lived, bone marrow) › IgA plasma cell (mucosal)
IgA plasma cell (mucosal)
IgA-secreting plasma cell of mucosal origin expressing CCR10 and beta7 integrin; ~40% of human BM PCs are IgA+.
Marqueurs (10)
| Gène | Polarité | Protéine | Niveau | Spécificité | Espèce | Références |
|---|---|---|---|---|---|---|
| IGHA1 | positif | IgA1 | mRNA, protein | défini | human | 18987362 35549406 |
| JCHAIN | positif | J chain | mRNA | défini | human | 35549406 18987362 |
| CCR10 | positif | CCR10 | mRNA, protein | enrichi | human | 18987362 14523388 |
| ITGB7 | positif | Integrin beta7 | mRNA, protein | enrichi | human | 18987362 |
| PRDM1 | positif | Blimp-1 | mRNA, protein | enrichi | human, mouse | 12150891 |
| SDC1 | positif | CD138 | mRNA, protein | enrichi | human | 18987362 |
| XBP1 | positif | XBP1 | mRNA, protein | enrichi | human, mouse | 12150891 |
| SELL | négatif | CD62L | mRNA, protein | sous-ensemble | human | 18987362 |
| IGHM | négatif | IgM | protein | exclusion | human | 35549406 |
| MS4A1 | négatif | CD20 | mRNA, protein | exclusion | human | 18987362 35549406 |