Index › Lymphoïde › Lymphocyte (lymphoid lineage root) › B cell (pan-B) › Plasma cell (long-lived, bone marrow)

Plasma cell (long-lived, bone marrow)

Terminally differentiated, non-dividing antibody-secreting cell in survival niches; human CD19- CD38hi CD138+.

Synonymes : long-lived plasma cell, bone marrow plasma cell, LLPC

Tissus : bone marrow, spleen

Cell Ontology : plasma cell · CL:0000786 (correspondance exacte) — A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producin

Marqueurs (16)

Sous-types

• Short-lived plasma cell
• Long-lived plasma cell (CD19-CD38hiCD138+)
• IgA plasma cell (mucosal)

Données curées avec références PubMed/DOI, licence CC BY 4.0. « Spécifique » est calculé sur la couverture de cet atlas : vérifiez dans la littérature citée. Version interactive avec filtres et comparaison.