Index › Lymphoïde › Lymphocyte (lymphoid lineage root) › B cell (pan-B) › Plasma cell (long-lived, bone marrow) › Long-lived plasma cell (CD19-CD38hiCD138+)

Long-lived plasma cell (CD19-CD38hiCD138+)

Human bone-marrow plasma cell subset containing PCs specific for antigens not encountered for over 40 years.

Tissus : bone marrow

Cell Ontology : long lived plasma cell · CL:0000974 (correspondance exacte) — A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow.

Marqueurs (8)

Données curées avec références PubMed/DOI, licence CC BY 4.0. « Spécifique » est calculé sur la couverture de cet atlas : vérifiez dans la littérature citée. Version interactive avec filtres et comparaison.